Ideal Cures Introduces – Natural Sodium alginate based delayed release formulations System

Ideal Cures Introduces – Natural Sodium alginate based delayed release formulations System

MUMBAI, INDIA (May 21st , 2012) – Ideal Cures Pvt. Ltd. an Indian research based pharmaceutical excipient organization will launch its newly developed delayed release delivery system Instanute DR in Vitafoods Europe in Geneva on 22nd May 2012. On pre-launch occasion Suresh Pareek, Managing Director (Ideal Cures) and one of the inventor said that, Instanute DR is a path breaking product for delaying the release of the active ingredients having wide applicability in nutraceutical, food and dietary supplement industry. Instanute DR is ready to use enteric coating product and will help in maintaining efficacy of the active ingredient which are sensitive to high acidic pH in stomach. Through the use of Instanute DR, scientists will be able to program the release profile of the active ingredients ranging from 20-120 minutes. This is the first time Alginic Acid based composition has been developed to delay the release of drugs by film coating.

Speaking to the research scientists Chetan Rajsharad, Vice-President R&D Ideal Cures India and one of the inventors based in Mumbai stated that, Instanute DR product is based on natural polymer which is GRAS compliance meeting all requirements at par with regulatory approvals.

Emphasizing Instanute DR product range Dario Luini, Area Manager Ideal Cures Europe, and also one of the inventor of the product mentioned that presently in Europe delayed release or enteric release is achieved by use of Shellac or Starch based product and there is no fully ready to use material available for industry. It is also noted by industry professionals that Shellac and Starch based product have many-many limitations in terms of production and as well as product stability and face strict evaluation approval for GRAS compliance status.

Instanute DR is already tested extensively on some products such as Mint Oil and Fish Oil soft-gel capsules exhibiting programmable release profile of 60 minutes to 120 minute. It has also been tested on Creatine and Chili extract tablets for control release profile of 45 minutes to 60 minutes. Instanute DR is also experimented successfully in herbal products, Ten Herb tablet was showing delayed release profile of 60 minutes to 120 minutes. Other volatile and less stable products like Vitamin B complex with Metionin combination displayed delayed release profile ranging 60 minutes, 100 minutes and 120 minutes depending on coating weight gain applied on tablets.

Instanute DR seems to be a major pinnacle breakthrough technology in comparison to shellac and starch based compositions. Some of the highly volatile multivitamin product might face stability issues using Shellac based product whereas Instanute DR will overcome the problem and could be used for tablets as well as soft-gel capsules, MUPS, caplets etc. for controlling release profile. Film formed through Instanute DR is insoluble at pH less than 3 and is soluble above pH 3, while other comparative product using pre-gelatinized starch, Shellac perform as just insoluble physical barriers.

The release of the active ingredient can be programmed to be either in stomach (after a pre-determined time interval) or in the intestine (after 2 hours of consumption by the patient – like enteric release). Thus the release of the active ingredient can be delayed from 20 minutes to 120 minutes. Instanute DR thus offers a flexibility of use at customer requirements to delay release in the range of 20-120 minutes.

With successful development of this product Ideal Cures fulfilled its promise to provide pinnacle performance product to Nutraceutical industry having wide applicability. Ideal Cures pvt. Ltd. driven by it VISION is commitment towards improvement in development of world class coating compositions, thereby improving standards of health care industry products.

Ideal Cures is self-sustaining Indian Organization with Global reach to more than 36 countries with subsidiary Ideal Cures Europe SRL, Europe.  Ideal Cures has three cGMP manufacturing plants in India providing world-class support to Indian as well as foreign pharmaceutical organizations. Ideal Cures Pvt. Ltd. is perceived as major alternate supplier for the film coating system by many multinational companies, which offers them superior technical services and support with competitive product prices. Ideal Cures has reputation of meeting quality requirement at par of pharmaceutical industry and regulatory bodies. Ideal Cures has spent a decade in its relentless pursuit of excellence in finding tailor-made excipients and coating solutions for solid dosage forms. From ready to use Film Coating Systems, Modified release Technologies, NDDS and Acrylic Pharma Polymers to Extended Cooling Boosters and Neutral Spheres.

Press Release by Mr. Suresh Pareek managing Director Ideal Cures Pvt Ltd., Mumbai, India

For further information please contact –

Customer Relations at Ideal Cures Pvt. Ltd.
Mail:- info@idealcures.co.in
Phone:- 91 22 42688700

Web:- www.idealcures.co.in

India HO and Technical Center:- A-223 to A-229, 2nd Floor, Virwani Industrial Estate, Off Western Express Highway, Goregaon (East), Mumbai-400 063, India

Europe SRL:- Ideal Cures Europe SRL, Via Quintiliano, 30 ; 20138- Milano Italy.

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Ideal Cures Pvt. Ltd. receives key US Patent for sodium alginate based aqueous film coating technology.

MUMBAI, INDIA (March 27th, 2012) – Ideal Cures Pvt. Ltd. founded and based in Mumbai announced on March 27th receiving of US Patent Number 8,123,849,  relating to aqueous film coating composition based on sodium alginate for application in pharmaceutical and Nutraceutical – tablets, caplets, pellets and granules. Inventive composition provides elegant glossy prompt release coating which does not retard release of active ingredient from the coated substrate. This is the first time an Indian pharmaceutical excipient manufacturing company has been granted US patent on ready-to-use film coating composition.

This raises Ideal Cures patent portfolio to Ten granted patents which includes Nine granted patents in India. Ideal cures also own a variety of intellectual property for film coating composition in pharmaceutical and Nutraceutical industry for Immediate and Delayed release technologies.

The patent covers the technology of a coating composition comprising sodium alginate with 20% Recon level, which will result in saving of upto 40% coating time for pharmaceutical and Nutraceutical industry as compared to compositions based on Hydroxy-Propyl-Methyl-Cellulose.

The technology will provide an excellent opportunity to pharmaceutical and Nutraceuticals industry worldwide to get rid of organic solvents like IPA and Methylene chloride which are toxic to environment and coating operators. This technology will protect tablets from moisture, sunlight, and other atmospheric conditions. Technology would also be a great help for Nutraceutical industry looking for use of Gras Status products in their formulation. Addition of colors in the composition will have a distinct advantage of creating brand identification for the user as well as smoothness in the finish would be helpful for easy passage of tablets in esophagus more particularly for bigger tablets.

The company has also filed a patent application based on a Sodium Alginate for a programmed timed release of active ingredients with pre-determined lag period. This is highly useful to active ingredients which are sensitive to acidic pH and degradation in stomach.

Speaking at a Novel Drug Delivery Symposium to bunch of scientists in Ideal Cures Lab Mr. Suresh Pareek (Managing Director and  one of the Inventor) emphasized that ‘849 technology will provide an excellent opportunity to Nutraceuticals industry to comply with the gras status film coating systems worldwide. While the others have been struggling to develop a coating composition based on Natural Polymer which will qualify for Gras Status, we are bringing tomorrow’s technology today. It definitely moves the bar ahead for the competition and will likely cause them to go back to the labs again.

This proves Ideal Cures commitment towards improvement in development of world class coating compositions, thereby improving standards of health care industry products.

Ideal Cures is an Indian company with international presence in more than 40 countries having it’s subsidiary company Ideal Cures Europe SRL, Europe and has three cGMP manufacturing plants. Ideal Cures Pvt. Ltd. is perceived as major alternate supplier for the film coating system by many multinational companies, which offers them superior technical services and support with competitive product prices. Ideal Cures has reputation of meeting quality requirement at par of pharmaceutical industry and regulatory bodies. Ideal Cures has spent a decade in its relentless pursuit of excellence in finding tailor-made excipients and coating solutions for solid dosage forms. From ready to use Film Coating Systems, Modified release Technologies, NDDS and Acrylic Pharma Polymers to Extended Cooling Boosters and Neutral Spheres.

Press Release by Mr. Suresh Pareek managing Director Ideal Cures Pvt Ltd., Mumbai, India

For further information please contact –

Suresh Pareek +912242688711 email: pareeksuresh@idealcures.co.in

Web:- www.idealcures.co.in

India HO and Technical Center:- A-223 to A-229, 2nd Floor, Virwani Industrial Estate, Off Western Express Highway, Goregaon (East), Mumbai-400 063, India

Europe SRL:- Ideal Cures Europe SRL, Via Quintiliano, 30 ; 20138- Milano Italy.

Ideal Cures Pvt Ltd. Introduction to Services, Facilities, Products and Specialties

Ideal Cures Launches INSTACOAT E Series Film Coating Systems Having Ultra-Fast Coating Offering Economical & Ecological Benefits

Brochure Insta coat E-series

In continuation with its efforts to support pharmaceutical industry with the innovative products for film coating of tablets, Ideal Cures Pvt. Ltd an India based excipient manufacturing organization, introduces a new line of film coating materials under the brand Instacoat E Series. The products in E Series are a complete solution to the customer’s expectations for an ideal material. The philosophy behind E Series is Economic and Ecological (environmental and user friendly).

New e-series is a range of high performance coating products developed under Instacoat brand and consist of four coating systems.

Instacoat EHP 250 High Performance Aqueous Film coating System
Instacoat EMB Efficient Moisture Barrier Aqueous Film Coating System
Instacoat EEN Optimized Weight Gain Hydro-alcoholic Enteric Film Coating System
Instacoat EHA High Adhesion Aqueous Film Coating System

This will be launched in the coming CPhI Mumbai (Nov’ 30 – Dec’ 2, 2011), at Booth G28, expert team of scientists will discuss product benefits. INSTACOAT EHP 250 is a single polymer (PVA- Poly-Vinyl Alcohol) based fully aqueous coating system. The best advantage offered by the material is that the coating can be completed in less than 50% of the time, currently required with best of the materials available in the market. The product will be moderately priced, which will be suited to practically all the drug substances. The energy and time requirements are going to be reduced to very low due to fast drying of the material and the process-ability at a very high concentration and faster spray rates. The moisture barrier offered by the film coating is going to be much superior, which should help people to review the packaging components for coat savings.

Other products in the E Series spectrum are EMB, EEN and EHA. EMB is specifically developed for exclusive moisture barrier properties for highly moisture sensitive drugs, as an aqueous and fast coating system. EEN is optimized enteric coating achieved with minimum weight gain for the enteric or delayed release products. EHA is a high adhesion, immediate release HPMC based film coating system. Therefore, disintegration time and dissolution rates of the tablets products are not affected with film coatings using EHP 250 and EMB. Upon experimentation, it was noted that disintegration of the EHP and EMB film coated tablet is not affected even at a coating weight gain upto 4%.

Process Parameters
for a trial lot of 2 
kg tablets in a 12”
conventional pan
EHP 250 
Aqueous
PVA Based
Aqueous
HPMC Based 
Aqueous
HPMC Based 
Organic Solvent
Reconstitution percentage (% w/w) 25 20 11 5
Spray Rate (g/min.) 4 4 4 10
Wt. of coating
dispersion sprayed (g) 200 250 455 1000
Total spray time
(mins.) 50 63 115 100
Proposed weight gain 2 – 2.5% 2 – 2.5% 2 – 2.5% 2 – 2.5%
(% w/w)
Inlet and Bed Temp.
(deg. C)
60-70; 40-42 60-70; 40-42 60-70; 38-42 55-60; 35-40
Pan Speed (rpm) 18 – 20 18 – 20 18 – 20 18 – 20
Air Pressure (kg/cm2) 2 – 3 2 – 3 2 – 3 2.5 – 3.5
Time Saved (%) 20% 57% 50%

Speaking on the pre-launch occasion at a gathering Mr. Suresh Pareek, Managing Director said that, “This 4th generation film coating system will define the new standards of film coating systems. While others have been stumbling to develop and copy the 3rd generation coating system, we are launching Instacoat E Series. It definitely moves the bar ahead for the competition and will likely cause them to go back to the labs yet again.”

Ideal Cures is confident of the wider acceptability of these products, where scientifically it has been evaluated that the products are going to have an improved stability, longer shelf life and significant savings coupled with productivity.

Ideal Cures is an Indian company with international presence in more than 40 countries having it’s subsidiary company Ideal Cures Europe SRL, Europe and has three cGMP manufacturing plants along with modern R&D facilities at Mumbai, Vasai (India) and Milan (Italy). Ideal Cures has spent a decade in its relentless pursuit of excellence in finding tailor-made excipients and coating solutions for solid dosage forms. From ready to use Film Coating Systems, Modified release Technologies, NDDS and Acrylic Pharma Polymers to Extended Cooling Boosters and Neutral Spheres.

The product portfolio comprises INSTACOAT ready-to-use film coating systems, INSTANUTE coating technology for nutraceuticals and dietary supplements, ECOPOL range of Pharma Acrylic Polymer’s, ECOCOOL brand of cooling compounds, ESPHERES range of sugar, MCC, silicon & calcium carbonate spheres.

Ideal Cures Pvt. Ltd

Customer Relations at Ideal Cures Pvt. Ltd.
+91 22 42688700
info@idealcures.co.in
or
www.idealcures.co.in

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This also applies in respect to any rights of third parties.Our information and advice do not relieve our customer of their ownresponsibility for checking the suitability of our products for the envisagedpurpose.

None of the products will be supplied to countries in whichit could be in conflict with existing patents. However the final responsibilitylies exclusively with the Buyer.

Ready to use Film Coating

Excellence in technology and cost leadership

This segment comprises of complete range in Film Coating Systems and consists of Products for Normal film Coating, Enteric Coating, Moisture Barrier Coatings, Sustained Release Products, Speciality Products such as Tablet polishing system, Taste Masking agents; Ready to use Flavoured Coating material.

INSTACOAT product range can serve the Pharmaceutical, Ayurvedic, Nutraceutical and Confectionery industry engaged in the manufacture of solid oral dosage forms.

The division specializes in producing Aqueous and non aqueous coating material and also providing the necessary technical support to the customers for conversion of organic coating systems to aqueous coating systems.